Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Good
Based on 10 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E(as d-Alpha Tocopherol)
268 mg
1,787%
Top Medical Research Studies
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
8
We explored how inducing heme oxygenase-1 (HO-1) could impact blood clot formation in a mouse model. Through a series of tests, we observed that mice treated with a HO-1 inducer showed a significant delay in thrombus formation.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
Read More
Most Useful Reviews
9
Period pain relief
10 people found this helpful
I began with 400iu per day and now take 800iu. Initially, at 400iu, I noticed a change in my period; the lumps seemed to disappear, the blood became bright red, and the quantity was appropriate. At 800iu, I experienced a complete relief from period pain.
Read More
9
Prevents blood clots
2 people found this helpful
Solgar is my favourite brand, known for excellent quality and packaging. I find the product helps prevent blood clots, enhances vascular elasticity, and improves skin and hair health. It also alleviates menopausal symptoms. Highly recommended!
Read More
9
Quick blood circulation
1 people found this helpful
I typically take multiple vitamins daily but hadn’t taken vitamin E for a year. After taking 400iu, I noticed significant improvement in my blood circulation, particularly in my cold hands and feet. It enhanced my sexual desire, skin, and general well-being.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
- All Researches
9
Our exploration focused on how tocotrienols, a form of vitamin E, influence blood clotting, especially in the context of risk factors like stroke. Using a canine model, we assessed the effects of tocotrienols on platelet aggregation and thrombus formation.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
Read More
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
We explored the effects of vitamin E and sesamin on blood pressure and blood clot formation using young rats prone to stroke. The rats were divided into four groups: a control group, a vitamin E group, a sesamin group, and a combination group for five weeks.
Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.
Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.
Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Read More
9
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
8
We explored how inducing heme oxygenase-1 (HO-1) could impact blood clot formation in a mouse model. Through a series of tests, we observed that mice treated with a HO-1 inducer showed a significant delay in thrombus formation.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Period pain relief
10 people found this helpful
I began with 400iu per day and now take 800iu. Initially, at 400iu, I noticed a change in my period; the lumps seemed to disappear, the blood became bright red, and the quantity was appropriate. At 800iu, I experienced a complete relief from period pain.
Read More
9
Prevents blood clots
2 people found this helpful
Solgar is my favourite brand, known for excellent quality and packaging. I find the product helps prevent blood clots, enhances vascular elasticity, and improves skin and hair health. It also alleviates menopausal symptoms. Highly recommended!
Read More
9
Quick blood circulation
1 people found this helpful
I typically take multiple vitamins daily but hadn’t taken vitamin E for a year. After taking 400iu, I noticed significant improvement in my blood circulation, particularly in my cold hands and feet. It enhanced my sexual desire, skin, and general well-being.
Read More
7.5
Stable blood pressure
3 people found this helpful
My blood pressure stabilised after taking vitamin E. I previously had a mild cerebral infarction and took aspirin, but I hoped to improve blood flow and eliminate blood clots. After starting at 200 IU and increasing to 400 IU, I've noticed improvements in blood circulation. My wife's headaches have almost vanished too.
Read More
7.5
Reduces arterial ridges
2 people found this helpful
Vitamin E seems to dissolve blood clots on arterial walls. I take it daily and highly recommend it.
Read More
Frequently Asked Questions
9
Quick blood circulation
1 people found this helpful
I typically take multiple vitamins daily but hadn’t taken vitamin E for a year. After taking 400iu, I noticed significant improvement in my blood circulation, particularly in my cold hands and feet. It enhanced my sexual desire, skin, and general well-being.
6
Reduced menstrual heaviness
3 people found this helpful
Although Solgar vitamin E is pricier, it’s top quality. Dealing with heavy periods for years, I've found that taking it for a year has significantly reduced blood clots and heaviness. I believe it also enhances my hair's shine and improves my complexion.
8
Acne improvement
I take two tablets daily for half a year, originally for blood flow. Remarkably, it's helped heal persistent acne after years of treatment. I noticed much less menstrual pain, with a more normal cycle.
9
Period pain relief
10 people found this helpful
I began with 400iu per day and now take 800iu. Initially, at 400iu, I noticed a change in my period; the lumps seemed to disappear, the blood became bright red, and the quantity was appropriate. At 800iu, I experienced a complete relief from period pain.
7.5
Improved skin health
3 people found this helpful
I consistently take 400IU. Vitamin E has noticeably improved my blood flow and skin condition, reducing blemishes. It's convenient as I find it challenging to eat enough vitamin E-rich nuts daily.
7.5
Stable blood pressure
3 people found this helpful
My blood pressure stabilised after taking vitamin E. I previously had a mild cerebral infarction and took aspirin, but I hoped to improve blood flow and eliminate blood clots. After starting at 200 IU and increasing to 400 IU, I've noticed improvements in blood circulation. My wife's headaches have almost vanished too.
7.5
Reduces arterial ridges
2 people found this helpful
Vitamin E seems to dissolve blood clots on arterial walls. I take it daily and highly recommend it.
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
7
We examined how vitamin E influences bleeding risks in patients with nonvalvular atrial fibrillation undergoing anticoagulant therapy. In our retrospective study of 566 patients, higher levels of serum vitamin E were associated with increased bleeding events.
Specifically, those who experienced bleeding had significantly higher vitamin E concentrations compared to those who did not. This suggests that elevated vitamin E may predict a higher risk of hemorrhage in patients taking anticoagulants, prompting the need for further research to clarify this relationship with newer medications.
Specifically, those who experienced bleeding had significantly higher vitamin E concentrations compared to those who did not. This suggests that elevated vitamin E may predict a higher risk of hemorrhage in patients taking anticoagulants, prompting the need for further research to clarify this relationship with newer medications.
7
We investigated how tamoxifen affects blood clots in a rat model, focusing on the potential benefits of vitamin E treatment. Our study involved four groups of rats, with one receiving vitamin E alongside tamoxifen.
While we noted endothelial proliferation linked to tamoxifen, vitamin E appeared to reverse this effect. Surprisingly, no significant reduction in thrombus formation was found compared to control groups. Overall, our findings suggest further exploration of vitamin E in conjunction with tamoxifen is warranted.
While we noted endothelial proliferation linked to tamoxifen, vitamin E appeared to reverse this effect. Surprisingly, no significant reduction in thrombus formation was found compared to control groups. Overall, our findings suggest further exploration of vitamin E in conjunction with tamoxifen is warranted.
9
Our exploration focused on how tocotrienols, a form of vitamin E, influence blood clotting, especially in the context of risk factors like stroke. Using a canine model, we assessed the effects of tocotrienols on platelet aggregation and thrombus formation.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
References
- Jafar Haeri SM, Dashti G, Mardani M, Rashidi B, Nikgoftar Fathi A, et al. Effect of Vitamin E on Apoptosis of the Endothelial Cells of the Carotid Arteries in Hypercholesterolemic Male Rabbits. ARYA Atheroscler. 2023;19:10. doi:10.48305/arya.2022.39175.2824
- Ho JI, Ng EY, Chiew Y, Koay YY, Chuar PF, et al. The effects of vitamin E on non-proliferative diabetic retinopathy in type 2 diabetes mellitus: Are they sustainable with 12 months of therapy. SAGE Open Med. 2022;10:20503121221095324. doi:10.1177/20503121221095324
- Ceran C, Aksam E, Aksam B, Yenidünya S, Suludere Z, et al. Tamoxifen-Related Thrombosis: An Experimental Study in Rat Venous Microvascular Anastomosis Model. Ann Plast Surg. 2017;78:213. doi:10.1097/SAP.0000000000000798
- Pastori D, Carnevale R, Cangemi R, Saliola M, Nocella C, et al. Vitamin E serum levels and bleeding risk in patients receiving oral anticoagulant therapy: a retrospective cohort study. J Am Heart Assoc. 2013;2:e000364. doi:10.1161/JAHA.113.000364
- Sasaki Y, Kobara N, Higashino S, Giddings JC, Yamamoto J. Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats. Nutr Res. 2011;31:784. doi:10.1016/j.nutres.2011.09.010
- Fahim MA, Nemmar A, Singh S, Hassan MY. Antioxidants alleviate nicotine-induced platelet aggregation in cerebral arterioles of mice in vivo. Physiol Res. 2011;60:695.
- Qureshi AA, Karpen CW, Qureshi N, Papasian CJ, Morrison DC, et al. Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries. Lipids Health Dis. 2011;10:58. doi:10.1186/1476-511X-10-58
- Ristow B. Preoperative use of alpha tocopherol does not increase the risk of hematoma in the face lift patient: a preliminary report. Plast Reconstr Surg. 2009;124:1696. doi:10.1097/PRS.0b013e3181b98a3a
- Ping-Chia L, I-Ju L, Yu-Ching L, Li-Ching C, Wen-Chung C. Substance P scavenger enhances antioxidant defenses and prevents prothrombotic effects on the rat lung after acute exposure to oil smoke. J Biomed Sci. 2009;16:58. doi:10.1186/1423-0127-16-58
- Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. Circulation. 2007;116:1497.
- Singh I, Turner AH, Sinclair AJ, Li D, Hawley JA. Effects of gamma-tocopherol supplementation on thrombotic risk factors. Asia Pac J Clin Nutr. 2007;16:422.
- Allman-Farinelli MA, Dawson B. Diet and aging: bearing on thrombosis and hemostasis. Semin Thromb Hemost. 2005;31:111.
- Noguchi T, Ikeda K, Sasaki Y, Yamamoto J, Yamori Y. Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2004;31 Suppl 2:S24.
- Miyamoto S, Kawano H, Takazoe K, Soejima H, Sakamoto T, et al. Vitamin E improves fibrinolytic activity in patients with coronary spastic angina. Thromb Res. 2004;113:345.
- Lindenblatt N, Bordel R, Schareck W, Menger MD, Vollmar B. Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo. Arterioscler Thromb Vasc Biol. 2004;24:601.
